Faculty

1989-1992 Ph.D., Chemistry, The Chinese University of Hong Kong, with Professor Henry N. C. Wong

1983-1986 M.S., Pharmaceutical Chemistry, Shenyang College of Pharmacy, with Professor Qihuai Chen

1978-1982 B.A., Pharmaceutical Chemistry, Shenyang College of Pharmacy

2011-Present Professor of Chemistry, Peking University-Tsinghua University Joint Center for Life Sciences (PTCLS)

2008-Present Professor of Chemistry, School of Chemical Biology and Biotechnology, Peking University

2002-Present Professor of Chemistry, Dept. of Chemistry, Peking University

2005-2008 Director of Chemistry, XTL biopharmaceutical Inc. NY

2001-2005 Co-founders and Director of Chemistry, VivoQuest Inc. NY

1998-2001 Institute Fellow, Dept. of Cell biology, Harvard Medical School

1995-1998 Assistant professor, Dept. of Chemistry, The Scripps Research Institute

1992-1995 Postdoctoral Fellow, Dept. of Chemistry, The Scripps Research Institute, with Professor K. C. Nicolaou

2018 Shenzhen mayor Award

Second prize of 2016 National Natural Science Award

2014 Yunnan Provincial Natural Science grand prize

First prize of natural science of Guangdong Province in 2014

2013 first prize of Shenzhen Natural Science

2013 south Guangdong hundred outstanding scholars Award (Guangdong Province)

2013 "zhouweishan" Synthetic Innovation Award (Chinese Chemical Society)

2011 editorial board member of "medchemcomm" magazine of Royal Society of Chemistry

2011 editorial board member of Springer magazine "natural products and bioprospecting"

2011 editorial board member of Wiley VCH "advanced synthesis & catalysis"

2011 editorial board member of "combinatorial science" magazine of American Chemical Society

2010 Wuxi pharmaceutical company life science Outstanding Award (gold medal)

2009 Peking University Baosteel excellent teaching award

2008 The Asian Core Program Lectureship Award, the Asian Cutting-Edge Organic Chemistry programs

2005 Lilly Science Achievement Award (China)

2004 National Science Fund for Distinguished Young Scholars Award

2000 National Science Fund for Distinguished Young Scholars Award

Natural products are the products of coevolution with humans, and are the material basis for maintaining the common existence of animals and plants in the biosphere. The structural diversity, important biological activities and structure-activity relationship of natural products represent the special position of natural products in drug research and development. Therefore, natural products must play an important role in life sciences and new drug research and development. This research group carries out total synthesis research around complex natural products with important activities, and is committed to developing efficient and novel synthesis methodologies and applying them to the total synthesis of complex natural products and small molecule compounds with biological activities, so as to provide a research basis for subsequent biomedical research and new drug development. This research group provides a good research platform for young chemists who love organic chemistry and dare to discover and create beauty from organic synthesis. The research direction of the research group includes (a) new synthetic methodology project (b) synthetic project (c) chemical genomics project.

1) Zhen Yang*, Navigating the Pauson–Khand Reaction in Total Syntheses of Complex Natural Products.Acc. Chem. Res.2021, 54(3), 556–568.

2) Jun Huang*, Tingting Cao, Zhongchao Zhang,Zhen Yang*, Semisynthesis of (−)-Bufospirostenin A Enabled by Photosantonin Rearrangement Reaction.J. Am. Chem. Soc.2022,144(6), 2479–2483.

3)  Zhongchao Zhang, Sijia Chen, Fu Tang, Kai Guo, Xin-Ting Liang, Jun Huang*,Zhen Yang*, Total Synthesis of (+)-Cyclobutastellettolide B.J. Am. Chem. Soc.2021,143(43), 18287–18293.

4) Xin-Peng Mu, Yuan-He Li, Nan Zheng, Jian-Yu Long, Si-Jia Chen, Bing-Yan Liu, Chun-Bo Zhao,Zhen Yang*, Stereoselective Synthesis of Cyclohepta[b]indoles by Visible-Light-Induced [2+2]-Cycloaddition/retro-Mannich-type Reactions.Angew.Chem. Int. Ed.2021,60(20), 11211-11216.

5) Wei Zhang, Zhenyu Zhang, Jun-Chen Tang, Jin-Teng Che, Hao-Yu Zhang, Jia-Hua Chen*,Zhen Yang*, Total Synthesis of (+)-Haperforin G.J. Am. Chem. Soc.2020,142(46), 19487–19492.