Educational Background
2011-2016 doctor at Sichuan University
2007-2011 Bachelor at Sichuan University
Work Experience
2025-Present assistant professor, School of chemical biology and biotechnology, Peking University
2020-2025 sailing scholar of Shenzhen Bay laboratory institute of Chemical Biology
2017-2020 postdoctoral fellow, University of Geneva, Switzerland
2016-2017 post doctoral fellow, State University of New York, USA
Awards and Honors
The Thieme Chemistry Journals award，2024
Guangdong Pearl River young top talent，2022
Shenzhen overseas high-level talent，2021
Research Interests
The research direction of this research group focuses on the frontier fields of modern organic synthetic chemistry, mainly including: 1) asymmetric catalytic synthesis, through the collaboration and innovation with visible light, transition metals and other multi catalytic systems, to develop green, efficient and atom economical new strategies for organic synthesis; 2) The precise activation and functionalization of inert hydrocarbon bonds focus on breaking through the regional and stereoselective transformation problems of simple hydrocarbon molecules; 3) The innovative methodology is applied to the total synthesis of natural products with important biological activities, and the modification and optimization of drug molecular structure. At the same time, the research group has carried out characteristic research in the synthesis and functional regulation of bioactive molecules, and is committed to the selective synthesis and structural transformation of polypeptides and sugars.
Representative Achievements
1) Hongkai Wang, Lijuan Song, Jing Huang, Fule Wu, Zhuang Yang, Yangbin Liu,* Yun-Dong Wu,* Xiaoming Feng,* Regiodivergent and Enantioselective Allylic C−H Alkylation of Allyl Ethers: Optimization, Scope, Mechanism and Application.Angew. Chem. Int. Ed.2025,64, e202500125.
2) Bin Qing, Zhuang Yang, Zhenwei Wu, Zichun Zhang, Yuqiao Zhou, Xinlong Yan, Yangbin Liu,* Xiaoming Feng,* Stereodivergent Construction of 3,3’-Disubstituted Oxindoles via One-Pot Sequential Allylation/Alkylation and Its Application to the Total Synthesis of Trigolute B and D.J. Am. Chem. Soc.2025,147, 7729−7740. (Cover Picture)
3) Liang Ge, Hongkai Wang, Yangbin Liu,* Xiaoming Feng,* Asymmetric Three-Component Radical Alkene Carboazidation by Direct Activation of Aliphatic C−H Bonds.J. Am. Chem. Soc.2024,146, 13347−13355.
4) Xuexue Chang, Fangqing Zhang, Shibo Zhu, Zhuang Yang, Xiaoming Feng,* Yangbin Liu,* Photoredox-catalyzed diastereoselective dearomative prenylation and reverse-prenylation of electron-deficient indole derivatives.Nat. Commun.2023,14, 3876−3888.
5) Yang Xu, Hongkai Wang, Zhuang Yang, Yuqiao Zhou, Yangbin Liu,* Xiaoming Feng,* Stereodivergent Total Synthesis of Rocaglaol Initiated by Synergistic Dual-metal-catalyzed Asymmetric Allylation of Benzofuran-3(2H)-one,Chem2022,8, 2011−2022. (ESI Highly Cited Paper)
1) Yang Bin Liu, Xiao Ming Feng, Xue Xue Chang, Indoline compounds, pyrrolido indoline compounds and their preparation, ZL202211668031.5
2) Liu, Yang Bin, Feng, Xiao Ming, Xu, The intermediates, derivatives, preparation and application of rocmilanol, ZL202111202605.5
