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Faculty

Modern biotechnology

Location: Home > Faculty > Modern biotechnology > Content

Dr.Xian Jiang

Position:PhD supervisor, Assistant Professor

Tel:

Email:jiangxian@szbl.ac.cn

Homepage of the research group:Jiangxianlab.com

Educational Background

2009-2014 Beijing Institute of life sciences, Tsinghua University; doctor

2005-2009 Beijing Normal University; bachelor


Work Experience

2022-now school of chemical biology and biotechnology, Shenzhen Graduate School, Peking University; assistant professor

2021-now Shenzhen Bay laboratory institute of neurological diseases; Distinguished researcher

2021 Howard Hughes School of medicine, Stanford University; Research experts

2017-2021 Howard Hughes School of medicine, Stanford University; Postdoctoral

2014-2017 Beijing Institute of life sciences, Tsinghua University; Postdoctoral


Awards and Honors

2022 Overseas Young Talents Program

2023 Female civilized post and advanced individual in post creation in Guangming District


Research Interests

Using a variety of technologies such as single-cell transcriptomics, electrophysiology, cell and molecular biology, the research group systematically and deeply analyzed the molecular and cellular mechanisms of memory and memory impairment, and explored the pathogenic mechanism of neurodegenerative diseases such as Alzheimer's disease, bringing new hope for the treatment of the above diseases.

Representative Achievements(*=equal contribution;#=corresponding author)

1) Jiang X, Sando R, and Südhof TC. Multiple signaling pathways are essential for synapse formation induced by synaptic adhesion molecules.Proc Natl Acad Sci U S A. January19, 2021 118 (3) e2000173118; doi.org/10.1073/pnas.2000173118.

2) Chen MB#,Jiang X#,Quake SR#, and Südhof TC*. Persistent transcriptional programs are associated with remote memory.Nature, 2020, 587:437-442. *these authors contribute equally #co-corresponding author. doi:10.1038/s41586-020-2905-5.

3) Sando R,Jiang X, and Südhof TC. Latrophilin GPCRs direct synapse specificity by coincident binding of FLRTs and teneurins.Science2019, 363(6429). doi:10.1126/science.aav7969

4) Jiang X, Li L, Ying Z, Pan C, Huang S, Li L, Dai M, Yan B, Li M, Jiang H, Chen S, Zhang Z, and Wang X. A Small Molecule That Protects the Integrity of the Electron Transfer Chain Blocks the Mitochondrial Apoptotic Pathway.Mol Cell2016, 63: 229-239. (Cover Story) doi:10.1016/j.molcel.2016.06.016

5) Jiang X, Jiang H, Shen Z, and Wang X. Activation of mitochondrial protease OMA1 by Bax and Bak promotes cytochrome c release during apoptosis.Proc Natl Acad Sci U S A. 2014, 111(41):14782-7. doi:10.1073/pnas.1417253111

Patents

The patent name:apoptosis inhibitors, patent number:US17/333033, year 2021, ranking 4.

Contact Us

Contact Person: Ms. Lu

Tel: +86-755-2603-3049

Fax: +86-755-2603-3174

EMAIL: luyanan@pku.edu.cn

Address: Peking University Shenzhen Graduate School Building F 203, Xili University Town, Nanshan District, Shenzhen (518055)

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