Educational Background
2009-2014 Beijing Institute of life sciences, Tsinghua University; doctor
2005-2009 Beijing Normal University; bachelor
Work Experience
2022-now school of chemical biology and biotechnology, Shenzhen Graduate School, Peking University; assistant professor
2021-now Shenzhen Bay laboratory institute of neurological diseases; Distinguished researcher
2021 Howard Hughes School of medicine, Stanford University; Research experts
2017-2021 Howard Hughes School of medicine, Stanford University; Postdoctoral
2014-2017 Beijing Institute of life sciences, Tsinghua University; Postdoctoral
Awards and Honors
2022 Overseas Young Talents Program
2023 Female civilized post and advanced individual in post creation in Guangming District
Research Interests
Using a variety of technologies such as single-cell transcriptomics, electrophysiology, cell and molecular biology, the research group systematically and deeply analyzed the molecular and cellular mechanisms of memory and memory impairment, and explored the pathogenic mechanism of neurodegenerative diseases such as Alzheimer's disease, bringing new hope for the treatment of the above diseases.
Representative Achievements(*=equal contribution;#=corresponding author)
1) Jiang X, Sando R, and Südhof TC. Multiple signaling pathways are essential for synapse formation induced by synaptic adhesion molecules.Proc Natl Acad Sci U S A. January19, 2021 118 (3) e2000173118; doi.org/10.1073/pnas.2000173118.
2) Chen MB#,Jiang X#,Quake SR#, and Südhof TC*. Persistent transcriptional programs are associated with remote memory.Nature, 2020, 587:437-442. *these authors contribute equally #co-corresponding author. doi:10.1038/s41586-020-2905-5.
3) Sando R,Jiang X, and Südhof TC. Latrophilin GPCRs direct synapse specificity by coincident binding of FLRTs and teneurins.Science2019, 363(6429). doi:10.1126/science.aav7969
4) Jiang X, Li L, Ying Z, Pan C, Huang S, Li L, Dai M, Yan B, Li M, Jiang H, Chen S, Zhang Z, and Wang X. A Small Molecule That Protects the Integrity of the Electron Transfer Chain Blocks the Mitochondrial Apoptotic Pathway.Mol Cell2016, 63: 229-239. (Cover Story) doi:10.1016/j.molcel.2016.06.016
5) Jiang X, Jiang H, Shen Z, and Wang X. Activation of mitochondrial protease OMA1 by Bax and Bak promotes cytochrome c release during apoptosis.Proc Natl Acad Sci U S A. 2014, 111(41):14782-7. doi:10.1073/pnas.1417253111
Patents
The patent name:apoptosis inhibitors, patent number:US17/333033, year 2021, ranking 4.